tyrosine and tryptophan residues in some proteins have been substituted with m-fluorotyrosine and 4-fluorotryptophan respectively, without any effects on the protein functions, and the 19F nuclei have been used as magnetic resonance.Nonprotein amino acids with no cytotoxicity have been known to be incorporated into proteins. any nonprotein amino acid can be chemically incorporated into peptides, provided that appropriate methods are designed for protecting the functional group.Understand the role of NPAAs and D-AA s in auto immune disease and aging, the determination of these NPAAs and D-AA s is required. These NPAAs and D-AA speculated to be related to auto immune disease and to aging.These amino acids, although never found in proteins, perform several biological important function.M.Prasad Naidu MSc Medical Biochemistry, Ph.D.
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